Rifabutin Is Inactivated by Mycobacterium abscessus Arr

نویسندگان

چکیده

Mycobacterium abscessus exhibits arr (ADP-ribosyltransferase)-dependent rifampin resistance. In apparent contrast, rifabutin (RBT) has demonstrated promising activity in M. infection models, implying that RBT might not be inactivated by Arr.

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2021

ISSN: ['0066-4804', '1070-6283', '1098-6596']

DOI: https://doi.org/10.1128/aac.02215-20